How will we crack the brain?

Adam J Calhoun in Medium:

ScreenHunter_959 Jan. 25 23.09If you would like see things straight out of a a science fiction movie, you should visit a neuroscience laboratory. Technology and science has advanced so quickly that I am not sure the public understands how advanced we are. Depending on the species, creating new transgenic animals — where you slip new genetic material into an organism — starts at ‘pathetically easy.’ During my PhD, there were days I would create the DNA for five or ten new transgenics in one go; creating the animals themselves was hardly a challenge. Light can be used as a physical force to move things around (“optical tweezers”). Scientists routinely create custom-made viruses to go forth into a chosen animal and label a precise set of neural cells. We can rain light down onto an animal to replay — or delete — memories. The recent creation of the CRISPR system allows genetic engineering to occur at unprecedented levels.

And the technology is advancing — fast. Things that seemed impossible five years ago are being commercialized right now. But for all that the brain is still largely a black box that we can prod and poke without understanding what it is actually doing, or how it got there. It begs us to ask the question: what are the directions neuroscience is heading to make a sense of this neural hydra?

More here.

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