Over at the Templeton Foundation, several thinkers, Steven Pinker, Christoph Cardinal Schönborn, Mary Midgley, Christopher Hitchens, and Stuart Kauffman among them, discuss the issue and give very divergent answers. Pervez Hoodbhoy:
Not necessarily.
But you must find a science-friendly, science-compatible God. First, try the pantheon of available Creators. Inspect thoroughly. If none fits the bill, invent one.
The God of your choice must be a stickler for divine principles. Science does not take kindly to a deity who, if piqued or euphoric, sets aside seismological or cosmological principles and causes the moon to shiver, the earth to split asunder, or the universe to suddenly reverse its expansion. This God must, among other things, be stoically indifferent to supplications for changing local meteorological conditions, the task having already been assigned to the discipline of fluid dynamics. Therefore, indigenous peoples, even if they dance with great energy around totem poles, shall not cause even a drop of rain to fall on parched soil. Your rule-abiding and science-respecting God equally well dispenses with tearful Christians singing the Book of Job, pious Hindus feverishly reciting the havan yajna, or earnest Muslims performing the salat-i-istisqa as they face the Holy Ka’aba. The equations of fluid flow, not the number of earnest supplicants or quality of their prayers, determine weather outcomes. This is slightly unfortunate because one could imagine joining the faithful of all religions in a huge simultaneous global prayer that wipes away the pernicious effects of anthropogenic global climate change.
Your chosen God cannot entertain private petitions for good health and longevity, prevent an air crash, or send woe upon demand to the enemy. Mindful of microbiology and physiology, She cannot cure leprosy by dipping the afflicted in rivers or have humans remain in unscathed condition after being devoured by a huge fish. Faster-than-light travel is also out of the question, even for prophets and special messengers. Instead, She must run the world lawfully and unto the letter, closely following the Book of Nature.