February 27, 2007
It Seems the Fertility Clock Ticks for Men, Too
When it comes to fertility and the prospect of having normal babies, it has always been assumed that men have no biological clock — that unlike women, they can have it all, at any age. But mounting evidence is raising questions about that assumption, suggesting that as men get older, they face an increased risk of fathering children with abnormalities. A number of studies suggest that male fertility may diminish with age.
It’s a touchy subject. “Advanced maternal age” is formally defined: women who are 35 or older when they deliver their baby may have “A.M.A.” stamped on their medical files to call attention to the higher risks they face. But the concept of “advanced paternal age” is murky. “If you look at males over 50 or 40, yes, there is a decline in the number of sperm being produced, and there may be a decline in the amount of testosterone,” Dr. Sokol said. But by and large, she added, “the sperm can still do their job.”
“The message to men is: ‘Wake up and smell the java,’ ” said Pamela Madsen, executive director of the American Fertility Association, a national education and advocacy group. “ ‘It’s not just about women anymore, it’s about you too.’ "
More here.
Posted by Azra Raza at 07:06 AM | Permalink























Comments
The article got the age of the male biological clock wrong by a decade. 35 is the age when genetic risk to the offspring becomes significant,
http://www.sciencedaily.com/releases/2002/10/021018080014.htm
"It makes sense that the mutations causing these diseases would occur more frequently in older men, and indeed that's what we saw for Apert syndrome," says Ethylin Jabs, M.D., director of the Center for Craniofacial Development and Disorders at Johns Hopkins.
Importantly, disorders linked to advancing paternal age begin to increase rapidly at about the same time as maternal risks increase -- age 33 to 35.
http://uwnews.washington.edu/ni/article.asp?articleID=2521
Posted by: Leslie Feldman | Mar 6, 2007 10:41:00 AM
Thank you for your interesting post!
I thought perhaps you may also find this related scientific study interesting to you:
Human Longevity and Parental Age at Conception
http://longevity-science.org/Parental_Age_2000.pdf
Posted by: Longevity Science | Apr 21, 2007 11:20:42 PM
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