July 25, 2005
Blood vessel drugs halt cancer growth
From The Harvard Gazette:
Nobody believed Judah Folkman when, in the 1960s, he claimed that the growth of cancers could be stopped, even reversed, by blocking the tiny vessels that feed them blood. Over the years, however, he has survived peer rejection of his theory, and gone on to develop drugs that did what he predicted they would do. In 1998, endostatin, one of several anti-blood-vessel growth drugs developed in his lab, was hyped by the media as a "cure" for many different cancers. A scant seven years later, Fortune magazine derided it as a "failure." Both statements turn out to be high exaggerations.
A related drug, called Avastin, was approved for use in the United States in February 2004. Since then, 27 other countries have OK'd it for treating colon cancer. Avastin is also being tested on patients with kidney, breast, and ovarian cancers. In addition, another blood-vessel-growth blocker, Tarceva, has been approved for treatment of lung cancer in the United States.
More here.
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The interesting scientific question is this: Why are these microscopic "hair like" blood vessels formed in cancer tumors and why does blocking them cause tumor shrinkage? Neither of these questions is addressed in this article. However, the answer is likely found by first understanding the fundamental nature of cancer cells as discovered and verified experimentally in the laboratory by the "greatest biochemist of the twentieth century", Otto H. Warburg, M.D., Ph.D., 1883-1970, the former head of the Max Planck Institute of Cell Biology in Germany.
Numerous other research scientists have been obstructed by the orthodoxy too. For example, Joe Gold, M.D. sought to use an inexpensive and readily available substance to "block the glycolic pathway".
The substance was Hydrazine Sulfate. In 1973 Dean Burk, Ph.D, "then the head of cell chemistry at the government's cancer center"...."met with top officials of Sloan-Kettering Institute in New York..."
From "The Cancer Industry" by Ralph W. Moss, Ph.D., page 191:
"Let me tell you this perfectly true story. There is nothing mystical or poetic about it-and I could give you many (such stories). A woman with Hodgkin's disease who had been flat on her back for seven weeks, who had no appetite and who had lost all her weight- a 'paper-thin' patient-took hydrazine sulfate. One week later she was shopping in the grocery store with her own bag; five days later she was spending most of the day in her garden. I don't give you that as any miraculous story-it is simply the plain truth (Burk, 1974)" If you want to read the obstruction and fraud in the "scientific" testing of this substance by the medical orthodoxy, Dr. Moss has about 24 pages dedicated to the subject in his book.
As far as reduction in tumor sizes and responses, another scientist Stanislaw Burzynski, M.D., Ph.D. was similarly obstructed by the FDA as documented in the book "The Burzynski Breakthrough" by Thomas D. Elias, 1st edition and 2nd edition.
By the way, the scientist, the late Dean Burk Ph.D. (1904-1988) was an extremely distinguished chemist, biochemist and plant physiologist with a Ph.D. from U.C. Berkeley in plant nutrition and Chemistry at age 23! He published hundreds of scientific papers (more than 250) and was a foreign member (since 1953) of "The Palace of Cell Physiology" as Dr. Warburg's Institute was called in Germany. One paper he wrote with a co-auhor in 1934 is the most frequently cited paper in biohemistry; It was rejected by six referees who were overruled by the editor, Arthur B. Lamb. There is a beautiful short biography of his life by Professor H. L. McKenney of the University of Kansas, available on the internet and also published in FLUORIDE, 22:3, 1989.
Posted by: Winfield J. Abbe | Jul 26, 2005 12:23:41 AM
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